The chemokine receptor CXCR4 and its ligand CXCL12 regulate leukocyte trafficking. homeostasis and functions and are potential therapeutic targets in many diseases such as HIV-1 infection and cancers. Here. we identified new CXCR4 ligands in the CERMN chemical library using a FRET-based high-throughput screening assay. https://www.spidertattooz.com/UMA-Sound-Lantern/