Episodes of inflammation and pain are predominant features of arthritic joint diseases. Drug delivery systems (DDS) could reduce inflammation and pain long-term without chances of infection upon multiple injections. To allow for long-term evaluation of DDS. we modified a previously published acute arthritis model by extending follow-up periods between flare-ups. https://www.nacrack.com/quick-find-PrimaLuna-EVO-400-Tube-Preamplifier-super-choice/