Genome editing is a set of techniques for introducing targeted changes in genomes. It may be achieved by enzymes collectively called site-directed nucleases (SDN). Site-specificity of SDNs is provided either by the DNA binding domain of the protein molecule itself or by RNA molecule(s) that direct SDN to a specific site in the genome. https://www.roneverhart.com/Medline-Guardian-Toilet-Safety-Frame-Fall-Prevention-Toilet-Rails/