Interactions With Benzodiazepines and Other CNS Depressants Inform patients and caregivers that potentially lethal additive effects could come about if acetaminophen and codeine phosphate tablets are used with benzodiazepines or other CNS depressants, together with alcohol, and never to employ these drugs concomitantly Except supervised by a healthcare supplier (see https://codeine.store/is-codeine-addictive/